The original convent and church of Santo Domingo, built in the 13th century, is found outside the walls of the city, but it was destroyed in 1589 during Sir Francis Drake’s siege on the city. Shortly afterwards, Philip II ordered it to be rebuilt within the walls on its present site. The church opened for worship in 1617 and in 1676 the chapel of Our Lady of the Rosary, patron saint of A Caruña, was completed. However, by the end of the 18th century, the church was already in such a bad state that the decision was taken to destroy it and erect the present building in 1762, following the project of the architect Fray Manuel de los Mártires. Nevertheless, the chapels of the Remedios and the Rosary have been preserved from the previous construction.
The architecture is notable for the baroque façade and especially the tower, which, built by Alberto Ricoy, gives the impression of being crooked as it is aligned with the axis of the church and not with the façade. Inside, the church is very bright, with a single nave and a beautiful dome in the transept that rises 26 metres. The Baroque altarpiece of the Rosary, made in 1688, is also of great value, with an interesting sculpture of the patron saint by the sculptor Mateo de Prado.